CompletedNot Applicable

The Efficacy and Safety of Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchymal Stem Cells in Infertile Women With Thin Endometrium or Endometrial Scarring

China20 participantsStarted 2018-09-10

Plain-language summary

The purpose of the study is to evaluate the safety and effectiveness of the collagen scaffold loaded with umbilical cord derived mesenchymal stem cells (UC-MSCs) in infetile women with thin endometrium or endometrial scarring.

Who can participate

Age range20 Years – 42 Years

SexFEMALE

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Inclusion criteria

✓. Infertile patients with clear fertility desires
✓. Diagnosed with thin endometrium or endometrial scarring for whom drugs and surgical interventions were ineffective
✓. 20-42 years old
✓. Normal ovarian function or with frozen embryos
✓. Willing to actively cooperate with postoperative follow-up

Exclusion criteria

✕. With abnormal chromosome karyotype
✕. With other uterine diseases including large intramural myomas, severe endometriosis, severe adenomyosis, severe congenital uterine malformations, endometrial tuberculosis, vaginitis and endometritis
✕. Systemic diseases: hypertension, diabetes, and so on
✕. Contraindications to pregnancy
✕. Contraindications to hormone replacement therapy
✕. Medical history of pelvic tumors or receiving pelvic radiotherapy
✕. Involved in other clinical studies
✕. Unable to adhere to the follow-up

What they're measuring

endometrial thickness

Timeframe: 12 months

Trial details

NCT IDNCT03592849

SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-01-31

View on ClinicalTrials.gov More Infertility, Female trials