TerminatedNot Applicable

Phosphodiesterase 4 Gene Variant and Salbutamol Response in Persistent Childhood Asthma

Stopped: Number of inclusioNs not reached

France99 participantsStarted 2018-11-23

Plain-language summary

This study is designed to investigate whether the Phosphodiesterase 4 gene variability could be implicated in the salbutamol responsiveness in asthmatic children.

Who can participate

Age range6 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children 6-18 years * Asthma: confirmed asthma symptoms (wheeze, cough, dyspnea, chest tightness) and evidence for variable airflow limitation (≥ 12% increase in post bronchodilator FEV1, or ≥ 20% decrease in FEV1 post methacholine) * Spirometry prescribed for follow-up * Airflow limitation: FEV1\<80% and/or FEV1/FVC \<80 pre-bronchodilator Exclusion Criteria: * no exclusion criteria

What they're measuring

pre- and post-bronchodilator VEMS value

Timeframe: Day 0

Trial details

NCT IDNCT03592212

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-11-14

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