Based on the Ultrasound Evaluating the Effect of Xiaozhong Fang Particles for Knee Osteoarthritic With Synovial Fluid

Inclusion Criteria: * 1\) the American Society of Rheumatology established the diagnostic criteria for knee OA in 2001; * 2\) Kellgren/Lawrence score of knee joint grade as I,II and early III. * 3\) According to "Principles of clinical guidance for new drugs of traditional Chinese Medicine ",diagnosed as "Xi Bi Disease". * 4\) Patients with informed consent. * 5)Blood and urine routine tests, liver and kidney functions, electrocardiogram were normal before recruitment. * 6\) Patients were not treated with NSAIDS drugs or hormone drugs, and no patients were treated with drugs related to this disease at least 2 weeks. Exclusion Criteria: * 1)Patients suffer from other rheumatic and metabolic diseases such as gout, rheumatoid arthritis, diabetes and so on. * 2\) Patients with knee joint inflammatory infection, such as suppurative and nonspecific. * 3)Patients accompanied by traumatic synovitis, Villonodular pigmented synovitis, synovial membrane of the knee is the main lesion. * 4\) Patients with informed consent. * 5)The color of joint fluid of patients' knees is pink or other color or cloudy; the white blood cell counts \> 1000 /mm3 or with crystal in the joint fluid. * 6)Patients blood RF \> 30IU/ml, ESR \> 20mm/h, CRP \> 10mg/L. * 7)Patients combined with severe cardiovascular, cerebrovascular, liver, kidney and other primary diseases and mental diseases.