ChordArt System for Mitral Regurgitation

Inclusion Criteria: * Age ≥ 18 years * Mitral Regurgitation due to degenerative mitral leaflet prolapse or flail * Left Ventricular Ejection Fraction \>20% * New York Heart Association functional class II to IV * Able and willing to give informed consent and follow protocol procedures. Exclusion Criteria: * Life expectancy \<1 year * Hemodynamic instability * Severe untreated ischemic disease * Pulmonary Hypertension * Any prior mitral valve surgery or transcatheter mitral valve procedure * Stroke or transient ischemic event within 30 days before randomization * Patient is pregnant (urine human chorionic gonadotropin (HCG) test result positive), planning to be pregnant or lactating. * Renal insufficiency * Acute anemia * Chronic obstructive pulmonary disease * Severe right ventricular dysfunction * Hepatic insufficiency * Patient is participating in other investigational studies