The primary purpose of the study is to identify clinical, radiological and genetic diagnostic criteria for Primary Failure of Eruption (PFE). The secondary purposes are to highlight the genotype-phenotype correlations in the PTHR1 and non-PTHR1 forms and analyze the therapeutic failures.
Age range
6 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Number of teeth
Timeframe: at inclusion (day 1)
Recording of dental caries
Timeframe: at inclusion (day 1)
Recording the location of dental caries
Timeframe: at inclusion (day 1)
Drugs intra uterine exposure
Timeframe: at inclusion (day 1)
Nutritional deficiencies
Timeframe: at inclusion (day 1)
Periodontium
Timeframe: at inclusion (day 1)
Oral hygiene
Timeframe: at inclusion (day 1)
Gingival inflammation
Timeframe: at inclusion (day 1)
Treatment needs
Timeframe: at inclusion (day 1)
Face shape
Timeframe: at inclusion (day 1)
Symmetry of the face
Timeframe: at inclusion (day 1)
Profile (shape)
Timeframe: at inclusion (day 1)
Smile
Timeframe: at inclusion (day 1)
Vertical dimension
Timeframe: at inclusion (day 1)
Transversal dimension
Timeframe: at inclusion (day 1)
Sagittal dimension
Timeframe: at inclusion (day 1)
Chewing
Timeframe: at inclusion (day 1)
Nasal breathing
Timeframe: at inclusion (day 1)
Swallowing
Timeframe: at inclusion (day 1)