CompletedNot Applicable

Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)

Norway, Sweden48 participantsStarted 2018-02-26

Plain-language summary

The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time (during the first year after the event), compared with a healthy control group. Brain function during cognitive tasks and emotion processing will also be studied using functional MRI (fMRI). Another aim is to study whether clinical outcomes such as PTSD, anxiety and depression can be correlated with cognitive function and whether health- related quality of life is affected after a cardiac arrest. The results from the cardiac arrest patient group will be compared with a healthy control group.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who have suffered a cardiac arrest of cardiac cause who were admitted to hospital after the event. * Age 18-70 * Consents to participating in the study Exclusion Criteria: * Terminal disease with expected survival \<1 year, moribund patient with \>1 treatment limitations. * A history of brain injury or brain disease that affects cognitive function, such as dementia * Severe psychiatric disorder, for example psychotic disorders or severe alcohol use disorder * Insufficient knowledge of the spoken language to understand instructions and answer questionnaires (oral or written) * Deceased within 1 month.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Cognitive function after cardiac arrest and changes over time

Timeframe: 2-6 weeks, 6 and 12 months post- cardiac arrest

Trial details

NCT IDNCT03579498

SponsorUppsala University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-08-26

View on ClinicalTrials.gov More Cardiac Arrest trials