Mycoprotein, Resistance Training, and Hypertrophy (NCT03572127) | Clinical Trial Compass
CompletedNot Applicable
Mycoprotein, Resistance Training, and Hypertrophy
United Kingdom42 participantsStarted 2018-05-16
Plain-language summary
Protein is vital for the preservation of health and optimal adaptation to training. However, animal proteins come with economic and environmental issues. The study will investigate the effect of non-animal vs animal based habitual protein consumption on muscle protein metabolism and changes in muscle mass and function over a longer period of time.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Males and females 18 - 40 years of age.
* Body mass index between 18 and 30.
* Recreationally active.
* Resistance training experienced (have previous performed resistance exercise, and are familiar with the basic movements).
Exclusion Criteria:
* Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes) (as this may affect normal protein metabolism).
* Any diagnosed cardiovascular disease or hypertension (to avoid any complications associated with heavy exercise).
* Elevated blood pressure at the time of screening. (An average systolic blood pressure reading of ≥140mmHg over two or more measurements and an average diastolic blood pressure of ≥90mmHg over two or more measurements.)
* Chronic use of any prescribed or over the counter pharmaceuticals (that may modulate muscle protein metabolism).
* A personal or family history of epilepsy, seizures or schizophrenia.
* Allergic to mycoprotein / Quorn, penicillin, or milk.
* Pregnancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at mycoprotein — a fungus-based protein — combined with resistance training to measure muscle protein synthesis, so could eating mycoprotein as part of my diet and exercise routine actually help me build muscle, and is that something worth discussing given my specific health situation?
2Since this trial has already been completed, would my doctor be able to help me find and interpret the published results, and what do those findings actually mean for someone in my position compared to using more conventional protein sources like whey or animal protein?
3The trial focused on muscle protein synthesis as its primary outcome, but I'm wondering whether that lab measurement actually translates into real-world muscle growth or strength gains that I'd notice — can my doctor explain the difference between measuring protein synthesis in a study and seeing practical results?
4Mycoprotein is a relatively uncommon dietary protein source — are there any safety concerns, allergies, or digestive issues my doctor thinks I should be aware of before I consider incorporating it into my diet alongside a resistance training program?
5Since this study was listed as phase NA, meaning it wasn't a standard drug trial, does my doctor think the evidence it generated is strong enough to inform a real dietary or exercise decision, or would they recommend I wait for larger or longer-term studies first?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.