Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure

Inclusion Criteria: * Successful transcatheter LAAC with any approved device * Age≥18 years old Exclusion Criteria: * Absolute contraindications for anticoagulation therapy * Absolute contraindications for antiplatelet therapy * End-stage renal disease (CrCl \<15 ml/min) * Recent percutaneous revascularization with drug-eluting stents requiring dual antiplatelet therapy * Prior intracranial hemorrhage * Contraindications for TEE * Severe pericardial effusion within the first 24 hrs following LAAC * Major/life-threatening bleeding event within the month prior to LAAC * Multiple bleeding events (minor or major) within the month prior to LAAC * Major/life-threatening bleeding within the first 24 hrs following LAAC