The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology. Data are collected regarding environmental factors, family and lifestyle, clinical experimental outcomes and imaging results of pregnant women and children from birth to 18 years old. Biological samples including blood and tissue samples are also collected from the children and their parents.
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Change of biometric parameter in centimeter of fetuses at the thirteenth week of gestational age
Timeframe: At every week from the thirteenth week of gestational age to delivery of babies
Weight in kilogram of neonate
Timeframe: At birth of neonate
Gene expression of husbands of pregnancy women
Timeframe: At 13 weeks of gestational age
Change of gene expression of pregnancy women
Timeframe: At 13, 26 and 34 weeks of gestational age
Result of Non-invasive Prenatal Testing
Timeframe: From 12 to 22 weeks of gestational age