CompletedNot Applicable

Optimization of PK/PD Target Attainment for Meropenem in Critically Ill Patients With Sepsis

116 participantsStarted 2012-08

Plain-language summary

WP1.1. PK/PD target attainment: Plasma exposure, Excretion via urine \& ELF exposure; WP1.2. Predictive dosing algorithm; WP1.3. ECMO subset

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Severe sepsis or septic shock * Admitted to an ICU ward * Treated with meropenem Exclusion Criteria: * eGFR(CKD-EPI) \< 70ml/min/1.73m² * Renal replacement therapy * Pregnancy * DNR code 1-3

What they're measuring

Risk factors for target non attainment

Timeframe: on day of sampling

Trial details

NCT IDNCT03560557

SponsorUniversitaire Ziekenhuizen KU Leuven

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-10

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