Repeated Transforaminal Anesthetic Injections With or Without Glucocorticoid in Patients With Cer… (NCT03541681) | Clinical Trial Compass
WithdrawnNot Applicable
Repeated Transforaminal Anesthetic Injections With or Without Glucocorticoid in Patients With Cervical Radiculopathy
Stopped: study lead could not proceed with the study due to changed employer
0Started 2021-06-01
Plain-language summary
The main objective is to evaluate pain and muscle strength in the upper extremities after treatment with cervical transforaminal injection of glucocorticoid vs. transforaminal injection of local anesthetic injection in patients with cervical radiculopathy. The investigators hypothesizes that there are correlations between radiculopathy and muscle weakness.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion Criteria:
Inclusion Criteria:
* People \>18 years and \<65, referred to the department of Neurosurgery in Lund, Sweden for evaluation and treatment of cervical radiculopathy.
* Patients with radiculopathy who after a diagnostic transforaminal injection with 0,5 ml Bupivacain local anesthetics reported a 50% or more reduction of radicular pain according to the visual analogue scale (VAS) (responders).
* Clinical findings and symptoms (i.e. radiculopathy, muscle weakness, sensibility disorder, reflexes) in the upper extremities, correlating to MRI verified nerve root compression on one single level between C4-C7 caused by spondylosis or disc herniation.
* Patients with positive, \>50% pain reduction, diagnostic transforaminal injection who choose conservative treatment as first option before surgery.
* Symptoms from dermatome/myotome radiculopathy \> 3 months, corresponding to MR-verified foraminal narrowing caused by disc herniation or foraminal stenosis from spondylosis/facet joint hypertrophy.
* Understanding the oral and written consent form in Swedish, and consenting to the study.
* Capable of adhering to the protocol.
Exclusion Criteria:
* Fibromyalgia or other general myalgia not suggestive of radicular pain.
* Cervical myelopathy caused by central spinal stenosis.
* Pain caused by stenosis 3 levels or more and/or disk herniation at 3 levels or more or cervical abnormalities (Klippel-Feil, Lytic/Sclerotic lesions, Recent fractures).
* Previously cervical su…