CompletedNot Applicable

Branched Chain Amino Acids Ratio in Medical Foods

Canada8 participantsStarted 2018-06-01

Plain-language summary

This study will evaluate the branched-chain amino acids (BCAA) ratio in the medical foods formulated for Methylmalonic and Propionic Acidemias (MMA/PROP) patients. We will recruit 6 healthy children between 6-10y (3 boys and 3 girls). They will be given amino acid-based shakes and protein free cookies. Using a minimally invasive stable isotope based technique, we will be able to determine the optimal ratio of BCAA to be added in the medical foods for the MMA/PROP subjects.

Who can participate

Age range6 Years – 10 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy school-aged children 6-10y * Normal weight * Normal eating habits * English speaking children Exclusion Criteria: * Children under 6 years old, or over 10 years old. * Children who are currently ill, with a fever, cold, vomiting or diarrhea. * Children outside of normal weight parameters (3rd -85th percentiles for weight). * Children with claustrophobia. * Children currently or recently taking medication or antibiotics. * Children with food allergies. * Children who cannot speak, write and read in English

What they're measuring

13C Phenylalanine Oxidation

Timeframe: 8 hours

Trial details

NCT IDNCT03539809

SponsorUniversity of British Columbia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-15

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