CompletedNot Applicable

RIPC During Free Flap With Preoperative Radiotherapy

South Korea44 participantsStarted 2018-05-29

Plain-language summary

Remote ischemic preconditioning (RIPC) has shown organ-protective effects in many clinical settings including patients with ischemic heart disease. However its protective role in head and neck cancer patients with preoperative radiotherapy undergoing free flap reconstructive surgery has not yet been evaluated. The purpose of the current study is to evaluate the effect of RIPC on tissue oxygen saturation and skin temperature of the flap.

Who can participate

Age range20 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult head and neck cancer patients undergoing free flap reconstructive surgery with preoperative radiotherapy Exclusion Criteria: * Radiotherapy within 4 weeks * Body mass index \< 18 kg/m\^2 or \> 35 kg/m\^2 * Presence of AV fistula at the arm, any reason to protect arms * Presence of vascular abnormality or discomfort at arms * Peripheral vascular disease, peripheral neuropathy, or coagulopathy * Uncontrolled diabetes mellitus * Preoperative use of beta-blockers * Refuse to enrol

What they're measuring

tissue oxygen saturation

Timeframe: postoperative day 1

Trial details

NCT IDNCT03535623

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-20

View on ClinicalTrials.gov More Ischemic Reperfusion Injury trials