Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Rand… (NCT03535337) | Clinical Trial Compass
CompletedNot Applicable
Adherence Interventions for HIV Youth Via Text & Cell Phone - Sequential Multiple Assignment Randomized Trial (SMART)
United States83 participantsStarted 2018-09-01
Plain-language summary
The purpose of this study is to test an adaptive adherence intervention, which utilizes two mobile health (mHealth) intervention designs, in an effort to promote adherence to antiretroviral therapy (ART) and achieve and maintain viral load (VL) suppression in youth living with HIV (YLH) while increasing understanding of the context for wide-scale implementation of cell phone support (CPS) and text messaging support (SMS), with and without incentives.
Who can participate
Age range
15 Years – 24 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* HIV diagnosis
* Viral load ≥ 200 copies/mL within 3 months prior to enrollment or self-reported adherence ≤ 80%
* ART medication regimen prescribed minimum of 3 months prior to eligibility VL or self-reported adherence
* Sole owner of device capable of sending/receiving calls and text messages
* Willingness to permit research team to communicate with their HIV care provider team
Exclusion Criteria:
* Mental, physical, or emotional capacity prevents completion of protocol as written
* Inability to understand written/spoken English
* Concurrent participant in any adherence behavioral research intervention
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial used text messages and cell phone-based tools to help young people with HIV stick to their medication — how does that kind of digital support compare to what's already available to me through your practice or my current care plan?
2The trial measured whether participants achieved an undetectable viral load, which is the goal of HIV treatment — based on where my viral load is right now, do you think a structured adherence support program like this one could make a meaningful difference for me?
3Since this trial is completed, have the results been published yet, and if so, what did they show about whether the text and phone-based approach actually improved medication adherence over 7 and 30 days?
4This study specifically focused on youth with HIV — given my age and situation, do you think the strategies tested here would still be relevant and practical for someone like me?
5Rather than looking into this trial now that it's done, are there similar active studies or adherence support programs I could join, or would you recommend focusing on standard care strategies first?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.