CompletedNot Applicable

Exercise and the Receptor for Advanced Glycation End Products (RAGE)

United States50 participantsStarted 2018-12-20

Plain-language summary

This study examines the effects of 12-weeks of aerobic exercise training on the mechanisms driving RAGE-mediated inflammation in type 2 diabetic humans.

Who can participate

Age range40 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 40-75 y * Type 2 diabetes * Overweight or obese (BMI 26-44 kg/m2) * Fluency in English (written and verbal) Exclusion Criteria: * Age \<40 or \>75 y * BMI \<26 or \>44 kg/m2 * Existing cardiovascular, cerebrovascular, renal, or hematological disease, or cancer * Current use of tobacco * Pregnant or lactating * Medications that may interfere with study outcomes

What they're measuring

Quantify the Percentage Change in Basal Circulating sRAGE After 12-weeks of Supervised Aerobic Exercise Training.

Timeframe: Baseline and 12 weeks

Trial details

NCT IDNCT03534687

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-08

Results submitted2024-05-07

View on ClinicalTrials.gov More Diabetes Mellitus, Type 2 trials