CompletedPhase 4

Preoperative Methadone Single Dose Reduces Postoperative Morphine Consumption.

Switzerland160 participantsStarted 2012-03

Plain-language summary

The aim of this study was to evaluate the effect of intraoperative methadone on postoperative analgesic requirements, pain scores and patient satisfaction in comparison to standard intraoperative pain control with fentanyl.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * informed consent * Patients of both genders and up to age 75 and ASA classification III were enrolled, when undergoing moderately to severely painful surgery scheduled for ≥90 minutes in general anaesthesia. * german speaking patients Exclusion Criteria: * patients including other studies * pregnant * breast feeding * patients in methadone substitution therapy * dependent drug user * patients with BMI greater than 36kg/m2 * patients with chronic or acute renal failure with serum creatinine greater than 400µmol/L * patients with liver insufficiency or failure * alcoholics * patients with acute heard attack

What they're measuring

Difference of postoperative morphine consumption

Timeframe: first 48 hours postoperatively

Trial details

NCT IDNCT03529032

SponsorKantonsspital Baden

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-07

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