Gaze and Postural Stability in Multiple Sclerosis (NCT03521557) | Clinical Trial Compass
CompletedNot Applicable
Gaze and Postural Stability in Multiple Sclerosis
United States42 participantsStarted 2018-05-29
Plain-language summary
In order to provide information that will improve therapy, the goals of this project are to determine if persons with MS with complaints of dizziness and at risk for falls can improve their balance and vision stability as a result of a bout of specific treatment. This project seeks to do this by conducting an experiment where people with MS are randomly assigned to a group that practices activities known to help improve inner ear function or a group that practices activities known to improve endurance and strength but that should not change inner ear function. Such a comparison will allow us to gain understanding of how the inner ear system is affected in MS and how it responds to treatment.
Who can participate
Age range
20 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Neurologist-diagnosed, clinically definite MS
* Expanded Disability Severity Scale (EDSS) score of less than 6.0
* Current complaints of dizziness (DHI \> 0)
* At risk of falls (determined by \> 2 falls in past year or Dynamic Gait Index \<19 or Activity Specific Balance Confidence Scale \<80
* Ability to tolerate repetitive 5 min bouts of angular head motions.
Exclusion Criteria:
* Central or Peripheral Nervous System disorders (other than MS)
* Otologic, Cervical spine, or lower extremity injury in last 12 months
* Exercise or alcohol use in last 48 hours
* Currently taking vestibular suppressant medications
* Peripheral Vestibular Pathology (BPPV, hypofunction, Meniere's disease
* Internuclear Opthalmoplegia
* MS exacerbation within last 8 weeks
* Orthopedic, neurologic, or cognitive comorbidities that would limit participation in the study procedures
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.