UnknownNot Applicable

Genetic Study for Infantile Onset Diabetes Mellitus

Egypt60 participantsStarted 2020-06-05

Plain-language summary

Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both.

Who can participate

Age range

2 Months – 1 Year

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diabetic patients with disease onset under the age of one year diagnosed according to American Diabetes Association criteria 2016 which include: * Fasting plasma glucose level at or above 7.0 mmol/L (126 mg/dl). * Plasma glucose at or above 11.1 mmol/L (200 mg/dl) two hours after a 1.75 gm/kg oral glucose load as in a glucose tolerance test. * Symptoms of hyperglycemia and random plasma glucose at or above 11.1 mmol/L 200 mg/dl). * Hemoglobin A1C at or above 48 mmol/mol. Exclusion Criteria: * Diabetic children with the disease onset above the age of one year. * Infants with transient hyperglycemia.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Evaluate possible risk factors among diabetic infants

Timeframe: within six months

Trial details

NCT IDNCT03519217

SponsorShimaa Kamal

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-05

View on ClinicalTrials.gov More Gene Mutation in Infantile Onset Diabetes Mellitus trials

Who can participate

Age range

2 Months – 1 Year

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.