Intraoral Appliance in the Treatment of Obstructive Sleep Apnea Syndrome in Obese

Inclusion Criteria: * BMI ≥40 kg/m² and ≤ 49,9 kg/m² * Female and male patients (Both of gender patients) with ages between 20 to 65 years old * Obstructive Sleep Apnea (OSA) diagnosis by polysomnography Exclusion Criteria: * sedative drugs users * Oxygen-dependent or decompensated lung disease * Decompensated congestive heart failure * Signs and symptoms of other sleeping disorders (narcolepsy, restless legs syndrome, insomnia) * craniofacial deformities carriers * previous OSAS Diagnosis and treatment * Active Oncological diseases in the last ten years * Patients with less than 8 teeth per arcade; * Patients with advanced periodontitis;