Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG (NCT03516929) | Clinical Trial Compass
CompletedNot Applicable
Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG
Egypt360 participantsStarted 2018-08-05
Plain-language summary
From our experience among Egyptian population in our institution, there is an increased prevalence of hidden subclinical peripheral artery disease along with carotid artery affection. Thus, increasing the risk of post-operative morbid complications.We aim to evaluate routine/ non-selective carotid and peripheral arterial screening in asymptomatic patients undergoing coronary artery bypass grafting in the Egyptian populationIt is a prospective, non-randomized, comparative study including two groups of patients. The study will start from the day of approval of the ethical committee. It will include 260 patients, on basis of "all new comers". Patients will be examined and classified as "high-risk" group (ɳ = 130) or "low-risk" group (ɳ=130).
All patients will have the "routine" preoperative investigations along with evaluation of extracranial carotid system by non-invasive carotid duplex and lower limb arterial system by non-invasive bilateral lower limb arterial duplex.
Who can participate
Age range35 Years – 75 Years
SexALL
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Inclusion criteria
✓. The acceptance of the patients to participate in the study in the form of a written consent.
✓. Patients of both sexes.
✓. Three vessels disease for CABG.
✓. Patients' age: from 35 to 75 years old.
✓. Elective, isolated, primary cases of CABG.
✓. Patients with ejection fraction above 40%.
✓. Inclusion criteria for the high-risk group will include:
✓. Patients with preoperative history of cerebrovascular events or symptoms suggestive of CVS eg.TIA, transient blindness in one eye, Dizziness, Confusion, Drowsiness, Headache, Temporary inability to speak or move.
Exclusion criteria
✕. Patients refusing to participate in the study.
✕. Age 76 years or above
What they're measuring
1
culprit pathology in carotid and / or lower limb duplex