The purpose of this study is to evaluate the relationship between insulin resistance (IR) and myocardial tissue abnormalities. The study will focus on a patient population, South Asians, with a high prevalence of IR.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Identifying patients with high fibrosis levels using peripheral blood samples
Timeframe: Blood samples drawn once at baseline visit
Insulin Sensitivity measured by OGTT
Timeframe: OGTT done at baseline/ first visit
Insulin Sensitivity measured by Fasting Lipid Panel
Timeframe: Lipid Panel done at baseline/ first visit
Left ventricular volume
Timeframe: CMR done at baseline visit
Left ventricular mass
Timeframe: CMR done at baseline visit
Ejection fraction %
Timeframe: CMR done at baseline visit
Myocardial tagging for strain analysis
Timeframe: CMR done at baseline visit
Assessing diffuse fibrosis via T1 mapping
Timeframe: CMR done at baseline visit
Assessing level of edema via T2 mapping
Timeframe: CMR done at baseline visit