CompletedNot Applicable

Intraoperative Neuromuscular Blockade and Postoperative Atelectasis

South Korea118 participantsStarted 2018-10-11

Plain-language summary

During one-lung ventilation in thoracic surgery, the intensity of neuromuscular blockade may change the compliance and resistance of ventilated lung, thereby affecting postoperative atelectasis. The present study investigated the effect of the intensity of intraoperative neuromuscular blockade on the postoperative atelectasis using chest computerized tomography in patients receiving thoracic surgery requiring one-lung ventilation.

Who can participate

Age range19 Years

SexALL

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Inclusion criteria

✓. Patients receiving scheduled unilateral lung lobectomy.
✓. Patients age ≥19
✓. Patients of American Society of Anesthesiologist Physical Status 1 or 2

Exclusion criteria

✕. Patients receiving bilateral lung lobectomy
✕. Patients BMI \> 35.0 or \< 18.5 kg/m2
✕. Patients of contraindicated to epidural patients controlled analgesia
✕. Patients with neuromuscular disease (i.e. myasthenia gravis)
✕. Patients with major burn (more than 3rd degrees)
✕. Patients with compromised cardiopulmonary function.

What they're measuring

Atelectasis Area on Chest CT

Timeframe: 1 day after the end of surgery

Trial details

NCT IDNCT03503565

SponsorKyung Hee University Hospital at Gangdong

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-05-14

Results submitted2021-06-24

View on ClinicalTrials.gov More Thoracic Surgery trials