CompletedNot Applicable

Safety and Efficacy of Midline and PICC

Canada293 participantsStarted 2018-07-01

Plain-language summary

The purpose of this study is to assess the non-inferiority for safety and efficacy of using Midline in comparison with PICC for intravenous therapy that do not require a central catheter.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Required intra venous therapy * Expected duration of the venous access: \> 6 days and \< 30days Exclusion Criteria: * Patient has a contraindication to insertion of either a Midline or a PICC relative to the therapy * Patient from other hospitals who come to the CHUM only for the installation of a central line * Decreased cognitive ability to care for device at home * Preexisting bacteremia (ie, existing positive blood cultures that had not been repeated with negative results) * Preexisting venous thrombosis or known hypercoagulable states (such as protein C or S deficiency, antithrombin deficiency, lupus anticoagulant) * Venous access with multiple lumens required * Patients not able to give informed consent * Prior participation to this study * Patient is enrolled in another investigational study * Patients hospitalized in the intensive care unit * Patients who are difficult to puncture and require multiple blood samples

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

% of patients without VAD-related adverse event requiring medical intervention

Timeframe: Until 1 week after VAD retrieval

% of patients whose intended or additional I.V treatments could be completed with the VAD without VAD complications, dysfunctions or limitations (ex: need for central access or for additional peripheral or central lumens/catheters)

Timeframe: Until 1 week after VAD retrieval

Trial details

NCT IDNCT03502980

SponsorCentre hospitalier de l'Université de Montréal (CHUM)

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-21

View on ClinicalTrials.gov More Vascular Access Devices trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

% of patients without VAD-related adverse event requiring medical intervention

Timeframe: Until 1 week after VAD retrieval