CompletedNot Applicable

Melatonin in Adults With SMS

France10 participantsStarted 2018-03-07

Plain-language summary

Sleep-Wake and behavioral disorders in Smith Magenis Syndrome (SMS) are strongly linked to an inversion of the nychtemeral secretion of melatonin. This inversion have been described in children with SMS. However its evolution during adulthood remains unknown. The aim of this study is to assess 24hours melatonin levels in 10 adults with SMS in order to optimize medication in adults with SMS

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient with Smith Magenis Syndrome aged 18 years or older * subject or guardian having signed the consent Exclusion Criteria: * Pregnant women * Minor subject * Diagnosis of Smith Magenis syndrome not certain * Taking benzodiazepines or related substances * Taking betablockers * Major behavioral disorders versus indicating participation in this study

What they're measuring

24h melatonin levels

Timeframe: 24 hours

Trial details

NCT IDNCT03492970

SponsorHôpital le Vinatier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-30

View on ClinicalTrials.gov More Smith Magenis Syndrome trials