Evaluation of endothelial glycocalyx damage in on-pump conventional coronary artery bypass surgery using a syndecan-1 (CD138) blood test. The study will be carried out in two stages. Pilot study for testing and correcting research methodology and the main study.
Age range
18 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Changes of syndecan-1 concentration during surgery and postoperative period.
Timeframe: 2 years
The evaluation of aortic clamping and on-pump duration on endothelial glycocalyx damage using syndecan-1 concentration measure.
Timeframe: 2 years
Assess the risk of early postoperative complications and find possible correlation to syndecan-1 concentration changes.
Timeframe: 2 years
The correlation of inflammatory status with glycocalyx damage.
Timeframe: 2 years
Glycocalyx damage to patients with diabetes vs non-diabetes during heart surgery.
Timeframe: 2 years