Not Yet RecruitingNot Applicable

Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage

China530 participantsStarted 2026-03-15

Plain-language summary

The purpose of this study is to determine whether treatment with remote ischemic conditioning is of sufficient promise to improve outcome before conducting a larger clinical trial to examine its effectiveness as a treatment for intracerebral hemorrhage.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age ≥ 18 years
✓. Supratentorial intracerebral hemorrhage confirmed by brain CT scan
✓. Functional independence prior to ICH, defined as pre-ICH mRS ≤ 1
✓. NIHSS score ≥ 4 and GCS ≥ 6 upon presentation
✓. Able to commence RIC treatment within 12 hours of stroke onset
✓. Signed and dated informed consent is obtained.

Exclusion criteria

✕. Definite evidence of secondary ICH, such as structural abnormality, brain tumor, thrombolytic drug, and other causes
✕. A very high likelihood that the patient will die within the next 24 hours on the basis of clinical and/or radiological criteria
✕. Already booked for surgical treatment
✕. Life expectancy of less than 90 days due to comorbid conditions
✕. Severe hematologic disease
✕. Concurrent use of anticoagulation drugs including Warfarin, dabigatran, rivaroxaban.
✕. Concurrent use of glibenclamide or nicorandil
✕. Any soft tissue, orthopedic, or vascular injury, wounds or fractures in healthy upper limb which may pose a contraindication for application of RIC

What they're measuring

Proportion of patients with Modified Rankin Scale (mRS) Score 0-2

Timeframe: 3 months

Trial details

NCT IDNCT03484936

SponsorYi Yang

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-15

Contact for this trial

Yi Yang, MD, PhD

0086-13756661217 doctor_yangyi@163.com

View on ClinicalTrials.gov More Intracranial Hemorrhages trials