CompletedNot Applicable

Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging

France100 participantsStarted 2018-11-07

Plain-language summary

The objective is the development and validation of morphological markers informative of aortic dilatation in order to improve the precision of the risk of aneurysm of the thoracic aorta and of acute aortic syndrome for patients with bicuspid aortic valve (BAV). The primary objective of this study is to demonstrate a correlation between the aortic local pulse wave velocity (PWV) measured with MRI and the progression of the thoracic aorta diameters measured by MRI after a follow-up of 2 years.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults over 18 years of age, * confirmed BAV by TTE computed tomography or MRI. * Adults benefiting from a social security scheme, * having received information on the research * having signed the consent form Exclusion Criteria: * Patient with a syndromic form of BAV: * Loeys-Dietz syndrome, * Turner syndrome * Williams-Beuren syndrome * Shone syndrome

What they're measuring

Evaluation of the progression of artic dilation with MRI

Timeframe: For each patient, inclusion in the study will be associated with one-day hospitalization with: MRI (=first MRI), TTE and UF (at T0). Patients will then be re-examined after 2 years to perform a second MRI to assess aortic dilatation (T=2 years).

Trial details

NCT IDNCT03474159

SponsorFrench Cardiology Society

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-24

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