Treatments and Outcomes of Untreated Cerebral Cavernous Malformations in CHina. (NCT03467295) | Clinical Trial Compass
UnknownNot Applicable
Treatments and Outcomes of Untreated Cerebral Cavernous Malformations in CHina.
China2,000 participantsStarted 2018-01-01
Plain-language summary
This nationwide multicenter prospective cohort study will collect the treatment information and outcomes of the patients with previously untreated cavernous malformations (U-CMs) in China (at least 2000 patients from 20 centers). The investigators aim to determine the effect of different treatments on long-term outcomes in patients with untreated cerebral cavernous malformations.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Definite diagnosis of cerebral CM on the basis of brain MRI or pathologic examination;
* Patients without any surgical intervention (microsurgery, radiosurgery, or multimodality treatment) before enrolment;
* Informed consent, and willing to accept long-term follow-up.
Exclusion Criteria:
* Patients receiving emergency surgery due to acute intracranial hematoma and resultant brain hernia;
* Patients with other never system diseases, such as aneurysms, tumors or other vascular malformations except venous development anomaly;
* Patients with severe underlying disease, which affects the patient's functional status and life expectancy;
* Patients with severe mental or psychologic disease.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Poor outcome
Timeframe: 3 years
Trial details
NCT IDNCT03467295
SponsorFirst Affiliated Hospital of Fujian Medical University