CompletedNot Applicable

Prematurity-Related Ventilatory Control

United States177 participantsStarted 2018-05-14

Plain-language summary

The purpose of this research study is to improve our understanding of unstable breathing and heart blood flow patterns seen in premature infants. The investigator will use novel non-invasive measures to understand the determinants of these unstable breathing and heart flow patterns to potentially identify new therapies for their prevention.

Who can participate

Age range1 Day – 28 Days

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All infants born between 24 0/7 and 28 6/7 weeks GA admitted to the Neonatal Intensive Care Unit at St. Louis Children's Hospital will be considered for enrollment. Exclusion Criteria: * Infants not likely to survive * Infant with significant heart disease * Infant with a significant congenital abnormalities of the central nervous system, nose, mouth lungs or ribs, or congenital diseases that affect lung growth * Physician refusal * Unlikely that the infant will be available for 52-week follow-up visit.

What they're measuring

Respiratory phenotype based on physiologic testing

Timeframe: 36 weeks post menstrual age

Trial details

NCT IDNCT03464396

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-02-09

View on ClinicalTrials.gov More Respiratory Control in Premature Infants trials