CompletedNot Applicable

The Efficacy and Safety of Intravesical Hyaluronic Acid and Chondroitin Sulfate After Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients

South Korea62 participantsStarted 2017-09-22

Plain-language summary

The efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate after transurethral resection of Hunner lesion in interstitial cystitis/bladder pain syndrome patients. To analyze the number and timing of recurrence based on a long-term follow-up.

Who can participate

Age range20 Years

SexALL

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Inclusion criteria

✓. Male and female aged 20 yrs or greater
✓. Patients diagnosed with Hunner lesion in IC(interstitial cystitis)/BPS(Bladder Pain Syndrome) and who is scheduled to undergo transurethral resection
✓. Symptom persisted more than 6 months
✓. Pain VAS ≥4

Exclusion criteria

✕. History of augmentation cystoplasty or previous transurethral coagulation/resection due to IC/BPS
✕. Child-bearing potential, pregnant or nursing women.
✕. Hematuria exceeds 1+ in the urinary dipstick (dipstick) examination.
✕. Urinary tract infection during run-in periods.
✕. Genitourinary tuberculosis or bladder,urethral and prostate cancer
✕. Recurrent urinary tract infection
✕. History of hysterectomy,mid-urethral sling,pelvic organ prolapse repair,vaginal delivery or Cesarean section,prostate operation or treatment etc within 6months.
✕. Neurologic disease history of cerebral infarction,multiple sclerosis or parkinsonism etc.-

What they're measuring

change in recurrence rate in Hyaluronic Acid and Chondroitin Sulfate instillation group after transurethral resection treatment

Timeframe: Every 3 months for 2 years

Trial details

NCT IDNCT03463499

SponsorSamsung Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-09-30

View on ClinicalTrials.gov More Interstitial Cystitis trials