WithdrawnNot Applicable

Unicompartmental Knee Arthroplasty (UKA) Versus Total Knee Arthroplasty (TKA) of Medial Osteoarthritis

Stopped: Lack of study funding

Canada0Started 2021-01

Plain-language summary

This study allows patients to take part of the decision making between a unicompartment knee (partial ) or a total Knee replacement . Using the measures of a decision aid questionnaire which explicitly details the risks and benefits of both procedures.The study will use subjective (reported by patient) and objective data (which will be measured) to allow the determination if one option is superior to the other. Information gathered from this study will be used to assist future patients in selecting the surgical option that best fits their life style. A feasibility pilot study of a randomized clinical trial will help to evaluate the outcomes of both procedures and help shape a multicentre Canadian study.

Who can participate

Age range50 Years – 80 Years

SexALL

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Inclusion Criteria:Inclusion criteria must and will be restricted to those patients who are generally considered candidates for UKA. Specific inclusion criteria will be restricted to patients: * Who report that most of their pain (greater than 75%) is located in the medial part of the knee on a regular basis. * With active range of motion from 10° of extension to 100° of flexion. * With an intact, competent, anterior cruciate ligament. * With overall limb alignment correctable to neutral, indicating a competent medial collateral ligament. * With radiographs showing primarily bone-on-bone disease in the medial compartment with minimal wear in both the lateral and patellofemoral compartments of the knee. * 50 to 80 years of age. * With a Body Mass Index (BMI) less than 40. For the secondary outcome of motion analysis, only patients exhibiting the following characteristics will be suitable for assessment: * BMI of 35 or less * No other ipsilateral or contralateral lower limb joint disorders Exclusion Criteria: * Those with inflammatory arthritis * Those with no fixed address * Those unable to commit to study requirements and follow-ups

What they're measuring

Change in Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index

Timeframe: 36 months

Trial details

NCT IDNCT03457051

SponsorOttawa Hospital Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09