Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease

Inclusion Criteria for participants with lung disease: * Male or female aged 18-85 years with diagnosed lung disease including but not limited to: asthma, emphysema, COPD, bronchiectasis, sarcoidosis, pulmonary fibrosis, alpha 1-anti-trypsin deficiency, eosinophilic granulomatosis with polyangiitis and bronchopulmonary dysplasia. * Subject understands the study procedures and is willing to participate in the study as indicated by the signature on the informed consent * Subject is judged to be in otherwise stable health on the basis of medical history * Able to read and/or understand English * Have a diagnosis of lung disease Inclusion Criteria for healthy volunteers: * Subjects male or female aged 18-85 years * Subject understands the study procedures and is willing to participate in the study as indicated by the signature on the informed consent * Subject is judged to be in otherwise stable health on the basis of medical history * Able to read and/or understand English * No current or previous history of respiratory infection or disease Exclusion Criteria: * Age \< 18 years or \>85 years * Pregnancy prior to or during study * In the opinion of the investigator, subject is mentally or legally incapacitated, preventing informed consent from being obtained, or cannot read or understand the written material * Patient is unable to perform spirometry or plethysmography maneuvers * Patient has an implanted mechanically, electrically or magnetically activated device or any meta…