CompletedPhase 2/3

Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway

France47 participantsStarted 2018-04-26

Plain-language summary

Identification of the cerebral fMRI phenotype of obese patients with FA in cognitive task context based on food choice making

Who can participate

Age range30 Years – 50 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * female * right-handed * grade 1 and 2 obesity * aged between 20 and 50 * no other addictions including smoking * no contraindications to fMRI * affiliated to French Social Security * having given a written informed consent Exclusion Criteria: * abdominal circumference + upper limbs along the body \> 200cm * addiction to alcohol or other psychoactive substances * daily smoker * sleep Apnea Syndrome paired * psychotic psychiatric disorders * history of bariatric surgery * medical care in the nutrition unit * inability to comprehend or complete questionnaires * pregnant or breastfeeding woman * persons subject to major legal protection (safeguarding justice, guardianship, trusteeship), persons deprived of liberty.

What they're measuring

Significant change in brain activity of the prefrontal cortex (area involved in the inhibitory control of food intake) measured by modification of BOLD (Blood-Oxygen-Level-Dependent) signal in fMRI during a cognitive task based on food choice making

Timeframe: Month 2

Trial details

NCT IDNCT03454711

SponsorRennes University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-08

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