CompletedNot Applicable

Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA

88 participantsStarted 2011-06-01

Plain-language summary

This study compares the neuroinflammatory response in patients with hypertensive ICH associated with IVH treated with intraventriculary applied rtPA, and the control group. The inflammatory mediator concentration is analyzed in local cerebrospinal liquor.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects with primary ICH with IVH * ICH score 2-4, , with origin of the hematoma in the basal ganglia and blood in the third and/or ventricle * Patient is not considered a surgical candidate by neurosurgery service Exclusion Criteria: * No history of diseases or drugs that affect the immunological system. * ICH score 1 and 5 * Current participation in another research drug treatment protocol * Previously known intracranial arteriovenous malformation or aneurysms * Intracerebral hematoma considered to be related to trauma * ICH is located in the pons * Blood in the subarachnoid space visualized on CT scan

What they're measuring

Cytokine concentration difference between two groups

Timeframe: Samples taken on day 0, day 1, day 3 and day 7.

Trial details

NCT IDNCT03452722

SponsorUniversity of Rijeka

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-08-01

View on ClinicalTrials.gov More Hypertensive Intracerebral Hemorrhage trials