Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception

Inclusion criteria

• . Good health as confirmed by medical history, physical examination, and clinical laboratory tests of blood and urine at the time of screening;
• . 18 to 50 years of age, at the enrollment visit;
• . BMI \< 33 kg/m2;
• . No history of androgen use in the six months prior to the first screening visit;
• . Agreement to use an effective method of contraception with his female partner (refer to Appendix 11 for acceptable forms of contraception) during the suppression and the first 7 days of the recovery phase and then only use the experimental method during the efficacy phase of the study;
• . In the opinion of the investigator, the male subject is willing and able to comply with the protocol, understand and sign an informed consent and HIPAA form;
• . The subject is legally competent, has been informed of the nature, the scope and the relevance of the study, voluntarily agrees to participation and the study's provisions and has duly signed the informed consent form (ICF);
• . Sexually active with a female partner (as specified below) with whom he has been in a stable, mutually monogamous relationship for at least 1 year prior to screening and with whom he intends to remain in a relationship for the duration of the study;

Exclusion criteria