CompletedNot Applicable

Olfactory Function and Delayed Neurocognitive Recovery

China131 participantsStarted 2018-01-01

Plain-language summary

To explore whether odor enrichment can reduce the risk of delayed neurocognitive recovery as an intervention strategy.

Age range65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. were aged at least 65 years old;
✓. were expected a postoperative hospital stay of at least 7 days;
✓. had American Society of Anesthesiologist (ASA) class I to II;
✓. were native Mandarin speakers;
✓. had been referred for a total knee or hip replacement under general anesthesia.

✕. were prior diagnosed of neurologic diseases by the International Statistical Classification of Diseases and Related Health Problems, 10th Revision (ICD-10);
✕. had a history of mental disorders diagnosed using the Diagnostic and Statistical Manual of Mental Disorders (DSM-5);
✕. had a history of illness or surgery with nasal or sinus;
✕. caught cold within one week;
✕. impaired vision or auditory function which may affect the assessments;
✕. were unwilling to comply with the protocol or procedures;
✕. did not pass the Mini-mental State Examination (illiterates get less than 18 points, primary school graduates get less than 20 points, secondary school graduates or higher get less than 24 points) .

Incidence of dNCR

Timeframe: 3 days before surgery (baseline) and 7 days after surgery (follow-up)

NCT IDNCT03441074

SponsorShanghai 10th People's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-31