SuspendedNot Applicable

Magnesium for Shivering in Epidural Lidocaine Deliveries

Stopped: Could not recruit patients

Canada90 participantsStarted 2018-06-11

Plain-language summary

Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia for Cesarean delivery.

Who can participate

Age range19 Years

SexFEMALE

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Inclusion criteria

✓. Gestational age of ≥37 weeks
✓. Women who are ≥ 19 years old
✓. Women undergoing Cesarean delivery under lidocaine top-up via a preexisting epidural catheter inserted for labor analgesia
✓. American Society of Anesthesiologist (ASA) Physical Status class 1 or 2

Exclusion criteria

✕. Emergency Cesarean delivery with limited time for informed consent
✕. Women who have received MgSO4 prior to study enrollment
✕. Indication for alternative mode of anesthesia for Cesarean delivery (e.g., general anesthesia)
✕. Medical conditions or medications that could lead to tremor or shivering. (e.g., movement disorder, untreated thyroid disease) or mask tremor or shivering (e.g., beta-blocker, benzodiazepine, anticonvulsants)
✕. Active shivering at time of recruitment
✕. Inability to read and understand English for the purpose of informed consent
✕. Contraindications to receiving MgSO4 (hypersensitivity reactions, respiratory rate \<16breaths/min, absent reflexes, urine output \<100 mL during the previous 4 hours, renal failure, or hypocalcemia)
✕. History of previous postpartum hemorrhage

What they're measuring

Incidence of intraoperative shivering

Timeframe: Through completion of cesarean surgical procedure (maximum 2 hours)

Severity of intraoperative shivering

Timeframe: Through completion of cesarean surgical procedure (maximum 2 hours)

Trial details

NCT IDNCT03439358

SponsorUniversity of British Columbia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09

View on ClinicalTrials.gov More Anesthesia trials