UnknownNot Applicable

Tissue-specific Effects of Insufficient Sleep

United States18 participantsStarted 2018-02-12

Plain-language summary

This study plans to learn more about how sleep loss impacts the way the body responds to sugar. This work will have important implications for development of treatments and countermeasures for people who are not able to get enough sleep for various reasons.

Who can participate

Age range18 Years – 35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Healthy, lean participants.
✓. No regular physical activity (\<20 minutes/day). No exercise will be allowed for 3 days prior to study start.
✓. Habitual sleep duration between 7-9.25h. Subjects must also be willing and able to keep a 9h time-in-bed schedule for 1 week prior to study admission.
✓. Potential subjects must have lived at Denver altitude or higher for at least 3 months to inpatient study.

Exclusion criteria

✕. Current or history of any clinically significant medical, psychiatric, or sleep disorder.
✕. Use or history of any drugs, medications, supplements, caffeine, and alcohol.
✕. Current or history of shiftwork in six months prior to laboratory study.
✕. Travel more than one time zone in three weeks prior to laboratory study.
✕. Blood donation in the 30 days prior to inpatient study.

What they're measuring

Change in insulin sensitivity

Timeframe: One week

Trial details

NCT IDNCT03437681

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-30

View on ClinicalTrials.gov More Healthy trials