Links Between Perception of Temporal Order Judgment and Causality in Schizophrenia (NCT03432000) | Clinical Trial Compass
TerminatedNot Applicable
Links Between Perception of Temporal Order Judgment and Causality in Schizophrenia
Stopped: Investigator departure
France52 participantsStarted 2018-02-01
Plain-language summary
People with schizophrenia show disturbances in the perception of time. Among these alterations are the perturbations of the temporal order judgment. They are characterized by the fact that, as opposed to the general population, people with schizophrenia require a longer time interval between two successive stimuli to estimate which of the two events appeared first. If these alterations are now well documented, their consequences remain little explored. Among these consequences could however appear distortions of the judgment of causality (likely to underlie certain delusional interpretations) as well as a distressing experience of loss of the continuity of the lived experience (that could contribute to the alterations basic of self-awareness).
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Subjects with schizophrenia:
* Age from 18 to 45 years
* Diagnosis of schizophrenia according to DSM V criteria
* French mother tongue
* Psychotropic treatment unchanged during the month preceding the inclusion
* Stable symptomatology
* Normal or corrected visual acuity (\> 0.8 at Snellen scale) and normal color vision
* Patients who gave informed consent to participate in the study
Control subjects (healthy volunteers):
* Age from 18 to 45 years
* Absence of neurological and psychiatric disorders
* French mother tongue
Exclusion Criteria:
* Recent addiction and abuse of cannabis or any other substance (according to DSM V criteria)
* Neurological disorders of vascular, infectious or neurodegenerative origin
* Taking somatic drugs with a cerebral or mental impact (eg corticosteroids)
* Disabling sensory disturbances, and in particular visual acuity
* Participation in a Neuro Cognitive Remediation Program
* Schizophrenia resistant to neuroleptic treatments
* Persons protected by law (pregnant women, minors, major under guardianship ...)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Comparison of the scores obtained by subjects with schizophrenia vs. the controls for the causal tasks, according to the delays between stimuli (stopping the moving launcher and appearance of the static object).