TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery

Inclusion Criteria: * : adult women admitted for a cesarean delivery before or during labor, at a term ≥ 34 weeks, * hemoglobin level at the last blood sample \>9g/dl, * available blood test for Hb and Ht within one week before caesarean delivery, * informed signed consent Exclusion Criteria: * previous thrombotic event or preexisting pro-thrombotic disease, * epileptic state or history of seizures, * presence of any chronic or active cardiovascular disease outside hypertension, * any chronic or active renal disease and chronic or active liver disease at risk thrombotic or hemorrhagic, autoimmune disease, * sickle cell disease, * placenta praevia, * placenta accreta/increta/percreta, * abruption placentae, * eclampsia, * HELLP syndrome, * significant hemorrhage before cesarean section * in utero fetal death, * administration of low-molecular-weight heparin or antiplatelet agents during the week before delivery, * planned general anesthesia, * hypersensitivity to tranexamic acid or concentrated hydrochloric acid, * instrumental extraction failure, * multiple pregnancy with vaginal delivery of the first child, * poor understanding of the French language.