RecruitingNot Applicable

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

United States48 participantsStarted 2018-06-21

Plain-language summary

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

Who can participate

Age range17 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 0 to \< 18 years old * Undergoing surgery at Boston Children's Hospital under general anesthesia * mechanically ventilated with an endotracheal tube * Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure Exclusion Criteria: * Prematurity * Low birth weight * Congenital heart disease * Left or right ventricular dysfunction * Cardiac arrhythmia * Pulmonary hypertension * Preoperative parenchymal or interstitial lung disease * Intracranial hypertension * Poor transthoracic acoustic window * Obesity * Allergy to ultrasound transmission gel * Need for single lung ventilation * Systemic hypertension on antihypertensive medications

What they're measuring

Change in stroke volume

Timeframe: immediately before and after each intervention

Trial details

NCT IDNCT03431064

SponsorBoston Children's Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12-31

Contact for this trial

Viviane Nasr, MD

617-355-6225 viviane.nasr@childrens.harvard.edu

View on ClinicalTrials.gov More Anesthesia trials