Demonstration of Carbonyl Stress on Hair Follicles (NCT03414476) | Clinical Trial Compass
CompletedNot Applicable
Demonstration of Carbonyl Stress on Hair Follicles
France40 participantsStarted 2018-03-26
Plain-language summary
In this study, the investigator will try to highlight the presence of carbonyl compounds in the hair follicles of women with telogen effluvium (ET) linked to stress of various origins (fatigue, infectious diseases, emotional stress ...).
Who can participate
Age range18 Years – 40 Years
SexFEMALE
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Inclusion Criteria:
Criteria related to the Population :
* Women aged from 18 to 40 ans (included)
* Phototype I Ã IV included, according to Fitzpatrick Classification
* Hair length 5 cm on the sampling area (centro-parietal part)
* Last shampoo at least 2 days before the inclusion visit, without application of styling product, care or water between this last shampoo and the inclusion
* Informed consent signature
Criteria related to the studied condition:
* ET group: hair loss related to various etiologies evaluated by a questionnaire according to the investigator's opinion and positive pull test (at least 3 hair collected per lock of 50 to 60 hair) AND
* Control group : no hair loss, evaluated by the questionnaire and negative pull test (less than 3 hair collected per lock of 50 to 60 hair)
Exclusion Criteria:
Criteria related to Population :
* Menopause
* Pregnancy, breastfeeding, childbirth for less than 6 months
Criteria related to Pathology :
For both groups:
* Alopecia causing hair loss on the upper part of the scalp
* Dermatological pathology or evolving cutaneous lesion in the scalp
* Control group only:
* Chronic unstabilized condition
* Acute evolving pathology
Criteria related to theTreatments :
For both groups:
* Use for at least 1 month of Minoxidil, Aminexil in the 3 months before inclusion or ongoing
* Systemic treatment affecting hair growth
* Any treatment or dietary supplement for antioxidant or capillary
Control group only:
* Treatment of gen…