Effect of Exercise on Genes That Control Muscle Function

Inclusion Criteria: * Age 20 - 40 years * BMI 18.5 - 29.9 * Stable body weight (not more than 2 kg change) during the past 6 months * Moderate sedentary (regular exercise less than 1 hour per week for the last 6 months) * Willing to provide informed consent Exclusion Criteria: * Failure to provide informed consent * Any major chronic disease or any condition that would interfere with exercise, in which exercise is contraindicated, or that would interfere with interpretation of results * Severe orthopedic and or neuromuscular disease that would contraindicate participation in exercise * Other significant co-morbid disease that would impair ability to exercise * Uncontrolled hypertension (BP greater than 160/90) * History of malignancy during the past 5 years * Diabetes mellitus as determined by self-report with verification (medical records, current treatment, confirmation from health care provider), or HbA1c of exceeding 6.5%