Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions

Inclusion Criteria: * ASA status I, II or III * Patients older than 18 years * Colonic surgery * Classical management of ERAS program patients in our center Exclusion Criteria: * Arrhythmia, abnormal electrocardiographic , antiarrhythmic therapy * Immunosuppressive treatments, corticosteroids or long-term NSAIDs (multiple weekly doses) or during preoperative 48 hours * conversion intraoperative of a laparoscopic surgical technique to a laparotomy technique * Pregnant women * Inability to complete the questions related to this study * Inability to use hydromorphone postoperative PCA * Intolerance or allergy to lidocaine, hydromorphone or any other drug that is included in the protocol for perioperative management Unexpected events leading to the exclusion: * Difficult unplanned intubation * Surgical complication requiring aggressive haemodynamic support (vasopressors, inotropes, transfusion)