Perception, Sensation, Cognition and Action in Humans (NCT03407066) | Clinical Trial Compass
RecruitingNot Applicable
Perception, Sensation, Cognition and Action in Humans
United States10,200 participantsStarted 2019-03-26
Plain-language summary
Background:
When people see and hear, the brain changes signals from the eyes and ears into perceptions and thoughts. No one fully understands how this happens. Researchers want to explore how healthy brains process sights and sounds.
Objectives:
To explore how people understand what they see and hear when the brain processes sights and sounds.
Eligibility:
Participants aged 13-65 who have at least 20/40 vision in at least one eye and do not use a hearing aid.
Design:
Some participants will take tests online anonymously. They will do computer tasks related to colors and behavior.
In-person participants will be screened with medical history and physical exam. They will complete questionnaires and vision and hearing tests.
Participants will plan how many testing sessions they will have and when. Sessions last 2-5 hours. They may include:
* Magnetic Resonance Imaging: Magnets and radio waves to take pictures of the brain. Participants will lie on a table that slides in and out of a tube. They will do a task during the scan.
* Magnetoencephalography: Records magnetic field changes from brain activity. Participants will sit or lie down. A cone will be lowered onto their head. They may do a task during the test.
* Electromyography: Electrodes attached to the skin will measure the electrical activity of muscles.
* Electroencephalogram: Electrodes on the scalp will record brain waves.
* Electrocardiography: Electrodes on the chest will record heart electrical activity.
* Tests of memory, attention, thinking, vision, and hearing.
* Eye Tracking: Cameras will follow participants eye movements. They may wear a cap with infrared cameras in front of their eyes.
During the sessions, participants vital signs may be monitored.
Who can participate
Age range
13 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
* INCLUSION CRITERIA:
Inclusion Criteria for In-lab Participants
A subject can be included in the in-lab portion of the study if he/she:
* is in good general health;
* is between 18 and 65 years old;
* has visual acuity of 20/40 in at least one eye (corrected with contact lenses is okay);
* has no hearing impairment requiring a hearing aid.
* is capable of understanding the procedures and requirements of this study;
* is willing and able to provide his/her own informed consent.
Inclusion Criteria for On-line Participants
A subject can be included in the on-line portion of the study if he/she:
* is in good general health;
* is between 18 and 65 years old;
* is capable of understanding the procedures and requirements of this study;
* is willing and able to provide his/her own informed consent.
Inclusion Criteria for Genetic Screening/Off-site Participants
A subject can be included in the off-site portion of the study if he/she:
* is between 13 and 65 years old;
* is in general good health;
* is capable of understanding the procedures and requirements of this study;
* is willing and able to provide his/her own informed consent.
EXCLUSION CRITERIA:
Exclusion Criteria for In-lab Participants
A participant is not eligible for participation in the in-lab portion of this study if any of the following exclusion criteria are present, as self-reported by the prospective participant or determined during clinical testing following consent:
* Participant is pregnant
* Particip…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.