Bearers of the sickle cell allele (S) are currently eligible for blood donations in Belgium. As blood donors are not tested for this allele, their heterozygous status is unknown. However, guidelines recommend to transfuse sickle cell patients with blood that is negative for the 'S' hemoglobin. To the investigator's knowledge, no study has been conducted to evaluate the impact of transfusion with blood originating from heterozygous donors on the transfusion performance and the improvement of clinical status of the sickle cell disease patients.
Sex
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Hemoglobin level -patient
Timeframe: 1 hour before blood transfusion
Hemoglobin level -patient
Timeframe: 1 hour after blood transfusion
% of 'S' type hemoglobin -patient
Timeframe: 1 hour before blood transfusion
% of 'S' type hemoglobin -patient
Timeframe: 1 hour after blood transfusion
Hemoglobin level - transfused blood
Timeframe: 1 hour before blood transfusion
% of 'S' type hemoglobin -transfused blood
Timeframe: 1 hour before blood transfusion
Transfusion yield
Timeframe: 1 hour after blood transfusion
Medical complications
Timeframe: 1 month
Length of stay
Timeframe: 1 month
Length of stay post transfusion
Timeframe: 1 month
Number of blood transfusions
Timeframe: 1 month
Hospital re-admission
Timeframe: 1 month
Mortality rate
Timeframe: 1 month.