Substrate Metabolism During Exercise Following Ingestion of Ethanol (NCT03404947) | Clinical Trial Compass
CompletedNot Applicable
Substrate Metabolism During Exercise Following Ingestion of Ethanol
United Kingdom8 participantsStarted 2017-11-13
Plain-language summary
This study will investigate how ethanol (pure alcohol) influences carbohydrate and fat metabolism during prolonged, moderate intensity exercise. Participants will perform two bouts of cycling exercise with or without prior ingestion of ethanol, in a randomised order, separated by one week.
Who can participate
Age range
18 Years – 30 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Habitual alcohol consumer (average 1-14 units per week)
* BMI 18.5 - 29.9 kg/m2
* Be able to attend the laboratory and willing to participate in necessary protocols
* Be willing to undertake the durations of the exercise protocol (2 hours) \]
* Have the capacity and willingness to provide informed consent (oral and written)
Exclusion Criteria:
* Non-or excessive alcohol drinkers (0 or \>14 units per week)
* History of substance abuse
* Habitual/previously habitual smokers
* BMI \>30.0 kg/m2
* Experience contraindications to the administration of the proposed anaesthetic (Lidocaine Hydrochloride)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in muscle glycogen content
Timeframe: Change in muscle glycogen content over 2 hours of moderate intensity cycling exercise
2
Blood glucose concentration
Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.
Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.