CompletedNot Applicable

Substrate Metabolism During Exercise Following Ingestion of Ethanol

United Kingdom8 participantsStarted 2017-11-13

Plain-language summary

This study will investigate how ethanol (pure alcohol) influences carbohydrate and fat metabolism during prolonged, moderate intensity exercise. Participants will perform two bouts of cycling exercise with or without prior ingestion of ethanol, in a randomised order, separated by one week.

Who can participate

Age range18 Years – 30 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Habitual alcohol consumer (average 1-14 units per week) * BMI 18.5 - 29.9 kg/m2 * Be able to attend the laboratory and willing to participate in necessary protocols * Be willing to undertake the durations of the exercise protocol (2 hours) \] * Have the capacity and willingness to provide informed consent (oral and written) Exclusion Criteria: * Non-or excessive alcohol drinkers (0 or \>14 units per week) * History of substance abuse * Habitual/previously habitual smokers * BMI \>30.0 kg/m2 * Experience contraindications to the administration of the proposed anaesthetic (Lidocaine Hydrochloride)

What they're measuring

Change in muscle glycogen content

Timeframe: Change in muscle glycogen content over 2 hours of moderate intensity cycling exercise

Blood glucose concentration

Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.

Blood non-esterified fatty acid (NEFA) concentration

Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.

Trial details

NCT IDNCT03404947

SponsorUniversity of Bath

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-06-29

View on ClinicalTrials.gov More Exercise Metabolism Following Ethanol Ingestion trials

Who can participate

Age range18 Years – 30 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in muscle glycogen content

Timeframe: Change in muscle glycogen content over 2 hours of moderate intensity cycling exercise

Blood glucose concentration

Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.

Blood non-esterified fatty acid (NEFA) concentration

Timeframe: Blood samples will be taken every 15 minutes during rest and the first hour of exercise, they will be taken every 30 minutes in the second hour of exercise.