Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease (NCT03399175) | Clinical Trial Compass
RecruitingNot Applicable
Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease
Brazil40 participantsStarted 2015-03-23
Plain-language summary
This prospective study will include patients with Vogt-Koyanagi-Harada disease from disease onset, treated with early systemic high-dose corticosteroid and immunosuppressive therapy. Clinical and subclinical signs of disease activity added with electroretinogram exams, through predefined intervals, will be evaluated through a minimum 12-month follow-up.
Who can participate
Age range
10 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is focused on early immunosuppressive therapy for Vogt-Koyanagi-Harada disease, can you explain what 'early' means in this context and whether my current stage of the disease would fit within that window?
2The trial is measuring scotopic electroretinogram results — which tests how the eye responds to light in dark conditions — so can you help me understand what that measure tells us about how VKH disease is progressing in my specific case?
3Since this trial is listed as Phase NA, meaning it may not follow the standard phase 1–3 safety and efficacy framework, what does that mean for what is already known — or not yet known — about the risks of the immunosuppressive treatment being studied here?
4Are there standard immunosuppressive treatments already used for VKH disease that I should consider first, and how would starting one of those compare to enrolling in this trial?
5If I were to discuss this trial with you seriously, what would the treatment schedule and follow-up visits look like, and is that something that would be realistic given my current situation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.