CompletedNot Applicable

HEart trAnsplantation Registry of piTie-Salpetriere University Hospital

566 participantsStarted 2009-01-01

Plain-language summary

Heart transplantation (HTx) is a procedure which is hindered by several complications. The HEARTS registry aims to allow the analysis of risk factors of all post-HTx complications. It consists in an exhaustive data collection at the moment of inclusion, i.e. HTx, knowing that patients underwent a full-fledged evaluation beforehand to evaluate their aptitude to being transplanted. Post-HTx complications include but is not limited to: all-cause mortality, AMR, ACR, CAV, AKI, sepsis, cancer, psychological disorders, metabolic disorders.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Heart transplantation Exclusion Criteria: * None

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

All-cause mortality

Timeframe: up to five years after inclusion

Acute cellular rejection (ACR)

Timeframe: up to five years after inclusion

Antibody mediated rejection (AMR)

Timeframe: up to five years after inclusion

Acute kidney injury (AKI)

Timeframe: up to five years after inclusion

Severe sepsis or septic shock

Timeframe: up to five years after inclusion

Cardiac allograft vasculopathy (CAV)

Timeframe: up to five years after inclusion

Trial details

NCT IDNCT03393793

SponsorLee S Nguyen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2015-12-31

View on ClinicalTrials.gov More Cardiac Transplant Disorder trials

Plain-language summary

What they're measuring

All-cause mortality

Timeframe: up to five years after inclusion

Acute cellular rejection (ACR)

Timeframe: up to five years after inclusion

Antibody mediated rejection (AMR)

Timeframe: up to five years after inclusion

Acute kidney injury (AKI)

Timeframe: up to five years after inclusion

Severe sepsis or septic shock

Timeframe: up to five years after inclusion

Cardiac allograft vasculopathy (CAV)

Timeframe: up to five years after inclusion