CompletedNot Applicable

Paracetamol and Metamizole With SPI-guided Anaesthesia for VRS

Poland165 participantsStarted 2018-01-15

Plain-language summary

The aim of this randomized trial is to assess the efficacy of preemptive analgesia using paracetamol or metamizole or both of them under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and vomiting) and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively. Patients will receive general anaesthesia combined with either preemptive analgesia using preemptive intravenous infusion of 1,0 g of metamizol or preemptive intravenous infusion of 1,0 g of acetaminophen or both of them together.

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion Criteria: * written consent to participate in the study * written consent to undergo general anaesthesia alone or combined with different techniques of pre-emptive analgesia and vitreoretinal surgery Exclusion Criteria: * history of allergy to local paracetamol or metamizole * necessity of administration of vasoactive drugs influencing SPI monitoring * pregnancy

What they're measuring

pain perception intraoperatively

Timeframe: intraoperatively

Trial details

NCT IDNCT03389243

SponsorMedical University of Silesia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-16

View on ClinicalTrials.gov More Vitreoretinal Surgeries trials